The final remaining relics Darkseid needed were being guarded by A.R.G.U.S. at their HQ, so Darkseid decided to use a Boom Tube to transport the building and all its contents to his base in the Amazon Rainforest. The Female Furies retrieved the relics and put them into place while Wonder Woman fought Darkseid. With the relics' power, Darkseid was able to open a portal to Themyscira. As it is impossible for one who has set foot on Themyscira to return after leaving, Diana was unable to follow Grail through the portal. Grail invaded and began transforming the Amazons into creatures resembling Darkseid's Parademons. As Jason had never actually set foot on Themyscira, he followed Grail and met his mother Hippolyta for the first time since his birth. While Jason and Hippolyta fought off the transformed Amazons, Wonder Woman was able to defeat Darkseid through her love for her deceased father, Zeus, and her half-siblings, calling their spirits out of Darkseid's body and destroying him from the inside. The Amazons captured Grail and imprisoned her in the prison beneath Themyscira, alongside Ares, while Darkseid re-emerged somewhere on Earth. Jason was gifted a magical spear from his mother and returned to Earth.
Steve Rose in The Guardian criticized the film for failing to explore the material's potential for "patriarchy-upending subversion". Peter Travers of Rolling Stone criticized the film's over-reliance on exposition: "Wonder Woman is hobbled by a slogging origin story and action that only comes in fits and starts. Just when Gadot and director Patty Jenkins...are ready to kick ass, we get backstory."
The chief chemist associated with General Ludendorff who specializes in chemistry and poisons. On her role, Anaya said, "Well, it was a small role in this big ensemble, but it is an important character in the story. I'm going to be a big nightmare" for Wonder Woman and Steve Trevor. Describing her character, Anaya said, "Dr. Maru loves rage and enjoys people's pain. She's creating terrible weapons, and her purpose in life is to kill as many people as possible, and provoke as much pain as possible". She researched World War I and Fritz Haber, the scientist who created mustard gas, to prepare for the role. On the character's facial scars, Anaya stated, "I went to Patty Jenkins and asked, 'What happened to her?' And she said, 'She did it on purpose.' I was like, 'What? Patty, you're going further than I ever imagined.' She said, 'She wants to provoke painful suffering, so she tested her own gas on her own face. She wanted to know how deep this form of her gas would go, so she put it on her own face.' You can see half of her face is completely gone. This is the sadistic side of Dr. Maru". She also stated her character "is quite the opposite to the lead role of this movie, one of the strongest characters ever of DC comics, Wonder Woman. I can tell you that Doctor Poison is someone with a capacity to provoke so much pain." On Dr. Maru's relationship with General Ludendorff, Anaya said, "I think that they have a relationship based on loyalty. Ludendorff is a very tormented General that lacks self-confidence. That's why, in part, he takes these drugs that Dr. Poison gives him. They are from different worlds, but they complement each other".
In May 2017, early tracking had Wonder Woman opening with $65–75 million, and possibly as high as $105 million. The film opened Friday, June 2, 2017, across 4,165 theaters and made $38.7 million on its opening day, including $3.7 million in IMAX. It was the biggest single-day gross for a woman-directed film, ahead of the $35.9 million opening Friday of Catherine Hardwicke's Twilight in 2008 and the biggest opening day for a woman-led comic book superhero film, ahead of Ghost in the Shell ($7 million). This included $11 million it made from Thursday previews, also the best start for a film directed by a woman, surpassing Fifty Shades of Grey's $8.6 million which was directed by Sam Taylor-Johnson, and the third-biggest of the year, behind Beauty and the Beast and Guardians of the Galaxy Vol. 2. Of that, $1.5 million came from IMAX screenings.